Issue
The outbox folder in a departmental mail account is holding onto mail objects and preventing new mall from going out. If you check on the send status and receive a Error 0x8004010F there is a likelihood the user has a corrupted Outlook profile.
Environment
This article applies to the Outlook for Windows.
Cause
In this case the issue was caused by a corrupted Outlook profile.
Resolution
For detailed steps on creating a new profile in Outlook review the official Microsoft article linked below. When you create a fresh profile and re-add the required accounts, new .OST files will be created fresh and pull down fresh copies of the objects from the cloud or server the client is talking to.
https://support.microsoft.com/en-us/help/2659085/error-0x8004010f-when-you-try-to-send-or-receive-email-in-outlook-2010
See Related Articles to the right for more information.